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| Titel | Protein kinase C |
| Verlag | (Wikipedia) |
| Datum | 19. May 2007 |
| URL | http://en.wikipedia.org/w/index.php?title=Protein_kinase_C&oldid=131926610 |
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| Fußnoten | no |
| Fragmente | 1 |
| [1.] Dsa/Fragment 019 24 - Diskussion Zuletzt bearbeitet: 2016-08-02 19:03:47 WiseWoman | Dsa, Fragment, Gesichtet, KomplettPlagiat, SMWFragment, Schutzlevel sysop, Wikipedia Protein kinase C 2007 |
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| Untersuchte Arbeit: Seite: 19, Zeilen: 24-34 |
Quelle: Wikipedia Protein kinase C 2007 Seite(n): 1 (online source), Zeilen: - |
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| Upon activation, protein kinase C enzymes are translocated to the plasma membrane by RACK proteins (membrane-bound receptor for activated protein kinase C proteins). The protein kinase C enzymes are known for their long-term activation: they remain activated after the original activation signal or the Ca2+-wave is gone. This is presumably achieved by the production of diacylglycerol from phosphatidylcholine by a phospholipase; fatty acids may also play a role in long-term activation.
Function The consensus sequence of protein kinase C enzymes is similar to that of protein kinase A, since it contains basic amino acids close to the Ser/Thr to be phosphorylated. Their substrates are MARCKS proteins, MAP kinase, transcription factor inhibitor IκB, the vitamin D3 receptor VDR, Raf kinase, calpain, and the EGF receptor. |
Upon activation, protein kinase C enzymes are translocated to the plasma membrane by RACK proteins (membrane-bound receptor for activated protein kinase C proteins). The protein kinase C enzymes are known for their long-term activation: they remain activated after the original activation signal or the Ca2+-wave is gone. This is presumably achieved by the production of diacylglycerol from phosphatidylcholine by a phospholipase; fatty acids may also play a role in long-term activation.
Function The consensus sequence of protein kinase C enzymes is similar to that of protein kinase A, since it contains basic amino acids close to the Ser/Thr to be phosphorylated. Their substrates are MARCKS proteins, MAP kinase, transcription factor inhibitor IκB, the vitamin D3 receptor VDR, Raf kinase, calpain, and the epidermal growth factor receptor. |
No source is given. |
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