B: Schematic representation of the homo- and hetero-dimeric structures of functional receptors for IL-6, G-CSF, GM-CSF and IL-2. The CRH domains containing the conserved cysteine residues (thin bars) and the WSXWS motif (thick bar) are indicated by shaded boxes. The gp130 (the β-chain of the IL-6 receptor) has a remarkable similarity to the
G-CSFR. The numbers indicate the percentage of identical amino acids in each subdomain23.
23. Basu S, Hodgson G, Katz M, Dunn AR. Evaluation of role of G-CSF in the production, survival, and release of neutrophils from bone marrow into circulation. Blood. 2002;100:854-861.
FIGURE 4. Schematic representation of the homo- and hetero-dimeric structures of functional receptors for IL-6, G-CSF, GM-CSF and IL-2. The CRH domains containing the conserved cysteine residues (thin bars) and the 'WSXWS' motif (thick bar) are indicated by shaded boxes. The gp130 (the β-chain of the IL-6 receptor) has a remarkable similarity to the G-CSF receptor as shown in Fig. 3. The numbers indicate the percentage of identical amino acids in each subdomain.
Anmerkungen
The source is not given. None of the copied material can be found in Basu et al. (2002)