Reconsolidation: Behavioural and Electrophysiological Sequelae of Context and Stress in Human Episodic Memory
von Dr. Jennifer L. Moore
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[1.] Jm/Fragment 072 13 - Diskussion Zuletzt bearbeitet: 2014-01-12 21:28:16 Graf Isolan | Fragment, Gesichtet, Jm, SMWFragment, Scanlon et al 2006, Schutzlevel sysop, Verschleierung |
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Untersuchte Arbeit: Seite: 72, Zeilen: 13-24 |
Quelle: Scanlon et al 2006 Seite(n): 6, Zeilen: 1st col: 20ff |
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However, and importantly in terms of present concerns, the major stumbling block encountered with the use of ERPs is the relatively poor spatial resolution it affords both Experimenters and clinicians. Electrical fields are significantly distorted by skull and scalp tissue, such that the pattern of activity recorded on the scalp may bear little resemblance to the regions of cortex responsible for such activity. As such, it is difficult to ascertain with convincing accuracy whether a potential recorded by a dorsolateral prefrontal electrode actually emanated from the dorsolateral prefrontal cortex. PET and fMRI allow for very high spatial resolution, given that the anatomical structures receiving increased blood flow can be represented in three dimensions. Also, because they do not rely on mere scalp recordings, activity in deep sub-cortical regions may also be observed. This disadvantage limits the use of ERPs in Experimental study, and many laboratories have conducted much research on methods to overcome this apparent deficit. | The major stumbling block encountered in the use of ERPs is the relatively poor spatial resolution it affords both experimenters and clinicians. Electrical fields are significantly distorted by skull and scalp tissue, so the pattern of activity recorded on the scalp may bear little resemblance to the regions of cortex responsible for such activity. As such, it is difficult to assert that a potential recorded by a dorsolateral prefrontal electrode emanated from the dorsolateral prefrontal cortex. PET and fMRI allow for very high spatial resolution, because the anatomical structures receiving increased blood flow can be represented in three dimensions. Also, because they do not rely on mere scalp recordings, activity in deep sub-cortical regions may also be seen. This disadvantage limits the use of ERPs in experimental study, and many laboratories have conducted much research on methods to overcome this apparent deficit. |
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Letzte Bearbeitung dieser Seite: durch Benutzer:Graf Isolan, Zeitstempel: 20140112213041
Letzte Bearbeitung dieser Seite: durch Benutzer:Graf Isolan, Zeitstempel: 20140112213041