The effects of somatostatin on spreading depression in rat neocortical tissues
von Cornelia Larissa Granz
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[1.] Clg/Fragment 015 01 - Diskussion Zuletzt bearbeitet: 2014-05-11 19:23:57 Schumann | BauernOpfer, Clg, Fragment, Garrett et al 1994, Gesichtet, SMWFragment, Schutzlevel sysop |
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Untersuchte Arbeit: Seite: 15, Zeilen: 1-10 |
Quelle: Garrett et al 1994 Seite(n): 389, Zeilen: left col. 6-9, 12-26 |
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The boundaries of the neocortical areas can be determined by the distribution pattern of neurons expressing somatostatin mRNA in rat neocortex. The occipital region was stratified, with intensely labelled cells for somatostatin in layers II/III and VI and faintly labelled cells in layer V. The parietal region carried a similar stratification, but more space between intensely labelled cells in layers III and V and between layers V and VI gave the region a three-tiered appearance. The temporal lobe displayed intensely labelled cells dispersed throughout layers III and VI and many in layer V as well as those faintly labelled without any differences among the laminae. The distribution of the cells hybridized for somatostatin mRNA formed two configurations within the frontal region. It was difficult to identify any lamination in the first area, whereas the second area demonstrated stratification reminiscent of the parietal region (Garrett et al., 1994). | Our investigation demonstrated that the boundaries of the neocortical areas can be determined by the distribution pattern of neurons expressing somatostatin mRNA. [...] The occipital region was stratified, with insensely labeled cells in layers II/III and VI and faintly labeled cells in layer V. The parietal region carried a similar stratification, but more space between intensely labeled cells in layers III and V and between layers V and VI gave the region a three-tiered appearance. The temporal region displayed intensely labeled cells dispersed throughout layers III and VI and many in layer V as well as those faintly labeled without any breaks between the laminae. The distribution of the cells hybridized for somatostatin mRNA formed two configurations within the frontal region. It was difficult to identify any lamination in the first area, whereas the second area demonstrated a stratification reminiscent of the parietal region, but with only two tiers. |
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