The effects of somatostatin on spreading depression in rat neocortical tissues
von Cornelia Larissa Granz
Statistik und Sichtungsnachweis dieser Seite findet sich am Artikelende
| [1.] Clg/Fragment 014 02 - Diskussion Zuletzt bearbeitet: 2014-05-10 23:28:47 Hindemith | Clg, Fragment, Gesichtet, SMWFragment, Schutzlevel sysop, Verschleierung, Wikipedia Somatostatin 2008 |
|
|
|
| Untersuchte Arbeit: Seite: 14, Zeilen: 2-12 |
Quelle: Wikipedia_Somatostatin_2008 Seite(n): 1 (online source), Zeilen: - |
|---|---|
| Somatostatin is produced by neuroendocrine neurons of the periventricular nucleus of the hypothalamus. These neurons project to the median eminence, where somatostatin is released from neurosecretory nerve endings into the hypothalamo-hypophysial portal circulation. These blood vessels carry somatostatin to the anterior pituitary gland, where somatostatin inhibits the secretion of growth hormone from somatotrope cells. The somatostatin neurons in the periventricular nucleus mediate negative feedback effects of growth hormone on its own release; the somatostatin neurons respond to high circulating levels of growth hormone by increasing the release of somatostatin. It is also produced by several other populations that project to other regions of the brain. In particular, there are populations of somatostatin neurons in the arcuate nucleus, the hippocampus and the brainstem nucleus of the solitary tract. | Somatostatin is produced by neuroendocrine neurons of the periventricular nucleus of the hypothalamus. These neurons project to the median eminence, where somatostatin is released from neurosecretory nerve endings into the hypothalamo-hypophysial portal circulation. These blood vessels carry somatostatin to the anterior pituitary gland, where somatostatin inhibits the secretion of growth hormone from somatotrope cells. The somatostatin neurons in the periventricular nucleus mediate negative feedback effects of growth hormone on its own release; the somatostatin neurons respond to high circulating concentrations of growth hormone and somatomedins by increasing the release of somatostatin, so reducing the rate of secretion of growth hormone.
Somatostatin is also produced by several other populations that project centrally - i.e. to other areas of the brain, and somatostatin receptors are expressed at many different sites in the brain. In particular, there are populations of somatostatin neurons in the arcuate nucleus, the hippocampus and the brainstem nucleus of the solitary tract. |
The source is not given. |
|
vorherige Seite | zur Übersichtsseite | folgende Seite
Letzte Bearbeitung dieser Seite: durch Benutzer:Hindemith, Zeitstempel: 20140510232945
Letzte Bearbeitung dieser Seite: durch Benutzer:Hindemith, Zeitstempel: 20140510232945