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MEHR ERFAHREN

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A new insight on direct actions of Granulocyte-Colony Stimulating Factor in the myocardium

von Ana Catarina Ribeiro Carrão

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[1.] Arc/Fragment 033 25 - Diskussion
Zuletzt bearbeitet: 2014-02-26 22:40:14 Schumann
Arc, BauernOpfer, Fragment, Gesichtet, Heil Schaper 2004, SMWFragment, Schutzlevel sysop

Typus
BauernOpfer
Bearbeiter
Hindemith
Gesichtet
Untersuchte Arbeit:
Seite: 33, Zeilen: 25-29
Quelle: Heil Schaper 2004
Seite(n): 450, Zeilen: r.col: 14ff
[The role of shear stress in collateral growth has been discussed extensively by Wolfgang Schaper’s research group and others91, 92. Their model is based on the following concept (Fig. 9):] After occlusion of an artery, the pressure in its distal stump falls to very low levels. When a vascular connection like a pre-existent collateral anastomoses [sic] exists between the high-pressure (proximal to the occlusion) and the low pressure (distal from the occlusion) region, a steep pressure gradient develops which increases blood flow through these connections.

91. Helisch A, Wagner S, Khan N, Drinane M, Wolfram S, Heil M, Ziegelhoeffer T, Brandt U, Pearlman JD, Swartz HM, Schaper W. Impact of mouse strain differences in innate hindlimb collateral vasculature. Arterioscler Thromb Vasc Biol. 2006;26:520-526.

92. Cai Z, Zhong H, Bosch-Marce M, Fox-Talbot K, Wang L, Wei C, Trush MA, Semenza GL. Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1{alpha}. Cardiovasc Res. 2008;77:463-470.

On occlusion of an artery, the pressure in its distal stump falls to very low levels. When a vascular connection like a preexistent collateral anastomosis exists between the high-pressure proximal to the occlusion with the low-pressure region distal from the occlusion, a steep pressure gradient develops which increases blood flow through these connections (Figure 1).
Anmerkungen

To be continued on the next page: Arc/Fragment 034 01

The authors of the source are mentioned, the source itself is not. The given sources Cai et al. (2009) and Helisch et al. (2006) do not contain the copied text.

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(Hindemith), WiseWoman



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