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| Untersuchte Arbeit: Seite: 19, Zeilen: 19-25 |
Quelle: Sheikh 2009 Seite(n): 23, 24, Zeilen: 23: 24ff - 24: 1-5 |
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| Increasing of potassium concentration may further impairs GABA mediated inhibition and leads to appearance of ictaform burst discharges. Higashima et al. (1996) have shown that activation of GABAergic mechanisms is necessary for the generation of afterdischarges recorded in hippocampal slices after electrical stimuli. Experimental and computational data obtained by Traub et al. (1996) also suggest a role played by GABAA-mediated depolarizing conductance in the epileptiform synchronization that occurs in some models of epileptiform discharge (in [particular that induced by 4AP application).] | Increasing of potassium concentration may further impairs GABA mediated inhibition and leads to appearance of ictaform burst discharges. Higashima et al. (1996) have shown that
[Seite 24] activation of GABAergic mechanisms is necessary for the generation of afterdischarges recorded in hippocampal slices after electrical stimuli. Experimental and computational data obtained by Traub et al. (1996) also suggest a role played by GABAA-mediated depolarizing conductance in the epileptiform synchronization that occurs in some models of epileptiform discharge (in particular that induced by 4AP application). |
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